Diffuse Large B-Cell Lymphoma of the Nasopharynx Presenting With Cluster-Like Headache.

Diffuse large B-cell lymphoma (DLBCL) is a primary malignant B-cell lymphoid neoplasm. The bulk of the disease develops in the Waldeyer ring (palatine tonsils, nasopharyngeal adenoids, base of the tongue, and lingual tonsils). DLBCL accounts for more than 50% of all Waldeyer ring lymphomas, which in turn account for about 15% of all head and neck lymphomas and about 50% of all extranodal head and neck lymphomas. The incidence of DLBCL is higher in Asian patients than in Western patients. Men are affected more often than women, and most patients present between the sixth and eighth decades of life. Patients with an underlying immunodeficiency disorder tend to pre-sent at a younger age.